Endocrine Abstracts

Background: TSH secretion shows a diurnal rhythm with a surge in the evening. The nocturnal surge is essential for thyroid function regulation. TSH surge is suggested to be blunted in central hypothyroidism. In idiopathic short stature (ISS), thyroid dysfunction has been suggested ranging from mild hypothyroidism to central hypothyroidism.Aim of the work: To study the pituitary thyroid axis and the TSH surge in ISS.Materials and me...